Free hepatology MCQ exam model for clinical students

Explanation:

• Altered mental status → Correct because ammonia toxicity affects brain function.

• Fever → Incorrect because it suggests infection.

• Ascites → Incorrect because it reflects portal hypertension.

• Jaundice → Incorrect because it reflects bilirubin metabolism.

• Hematemesis → Incorrect because it suggests variceal bleeding.

Explanation:

• Liver → Correct because hepatology is the study of liver diseases and their management.

• Pancreas → Incorrect because this is mainly gastroenterology/endocrinology.

• Gallbladder only → Incorrect because hepatology is not limited to gallbladder.

• Intestines → Incorrect because this is gastroenterology.

• Spleen → Incorrect because this is hematology-related.

Explanation:

• Hepatitis A virus → Correct because it is the most common cause of acute viral hepatitis globally.

• Hepatitis B virus → Incorrect because it commonly causes chronic hepatitis.

• Hepatitis C virus → Incorrect because it is usually chronic.

• Hepatitis D virus → Incorrect because it requires HBV co-infection.

• Hepatitis E virus → Incorrect because it is common but less than HAV.

Explanation:

• Prothrombin time → Correct because clotting factors are synthesized by the liver.

• Serum bilirubin → Incorrect because it reflects excretory function.

• ALT level → Incorrect because it reflects hepatocyte injury.

• AST level → Incorrect because it is not specific for synthesis.

• Alkaline phosphatase → Incorrect because it reflects cholestasis.

Explanation:

• Hepatitis B virus → Correct because it is the leading cause of chronic hepatitis worldwide.

• Hepatitis A virus → Incorrect because it does not cause chronic infection.

• Hepatitis E virus → Incorrect because it is usually acute.

• Alcohol → Incorrect because it causes alcoholic liver disease, not chronic hepatitis per se.

• Drug-induced liver injury → Incorrect because it is less common.

Explanation:

• Hepatitis B virus → Correct because it directly increases HCC risk even without cirrhosis.

• Hepatitis A virus → Incorrect because it does not cause chronic liver disease.

• Hepatitis E virus → Incorrect because it is usually self-limiting.

• Cytomegalovirus → Incorrect because it affects immunocompromised patients.

• Epstein–Barr virus → Incorrect because it is linked to lymphomas.

Explanation:

• Alanine aminotransferase → Correct because ALT is most specific to hepatocytes.

• Alkaline phosphatase → Incorrect because it rises in cholestasis and bone disease.

• Gamma-glutamyl transferase → Incorrect because it is sensitive but not specific.

• Creatine kinase → Incorrect because it reflects muscle injury.

• Lactate dehydrogenase → Incorrect because it is non-specific.

Explanation:

• 2 mg/dL → Correct because scleral icterus appears at this level.

• 0.5 mg/dL → Incorrect because it is within normal range.

• 1 mg/dL → Incorrect because jaundice is not visible yet.

• 5 mg/dL → Incorrect because jaundice appears earlier.

• 10 mg/dL → Incorrect because jaundice is already marked.

Explanation:

• Lactulose → Correct because it reduces ammonia absorption by acidifying the colon.

• Omeprazole → Incorrect because it reduces gastric acid.

• Propranolol → Incorrect because it prevents variceal bleeding.

• Octreotide → Incorrect because it is used in variceal hemorrhage.

• Rifaximin only → Incorrect because it is an adjunct, not first-line alone.

Explanation:

• Liver cirrhosis → Correct because fibrotic distortion increases portal resistance.

• Budd–Chiari syndrome → Incorrect because it is a rare cause.

• Right-sided heart failure → Incorrect because it causes congestive hepatopathy.

• Portal vein thrombosis → Incorrect because it is less common.

• Schistosomiasis → Incorrect because it is region-specific.