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Program of entrance examinations for discipline “Biological Systems” for medical faculties at Sechenov University

Program of entrance examinations for discipline “Biological Systems” for medical faculties

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Biology as a science. Methods of scientific knowledge

  • Biology as a science, its achievements, methods of understanding living nature.
  • Role biology in the formation of the modern scientific picture of the world
  • Level organization and evolution.
  • The main levels of organization of living organisms nature: cellular, organismic, population-species, biogeocenotic, biosphere.
  • Biological systems. General features of biological systems: cellular structure, features of chemical composition, metabolism and energy conversion, homeostasis. irritability, movement, growth and development, reproduction.
  • Evolution.

The cell as a biological system

  • Modern cell theory, its main provisions, role in the formation modern natural science picture of the world.
  • Development of knowledge about the cell.
  • The cellular structure of organisms is the basis of the unity of the organic world, proof of the relationship of living nature.
  • Diversity of cells.
  • Prokaryotes and Eukaryotes.
  • Comparative characteristics of plant, animal, bacteria, and fungi cells.
  • Chemical composition of the cell. Macro- and microelements.
  • The relationship between the structure and functions of inorganic and organic substances (proteins, nucleic acids, carbohydrates, lipids, ATP) that make up the cell.
  • The role of chemicals in the cell and the human body.
  • Structure cells.
    • The relationship between the structure and functions of parts and organelles of the cell is the basis its integrity.
  • Metabolism and energy transformations are properties of living organisms.
    • Energy metabolism and plastic metabolism, their relationship.
    • Stages of energy metabolism.
    • Fermentation and respiration.
  • Photosynthesis, its importance, cosmic role.
    • Phases of photosynthesis.
    • Light and tempo reactions of photosynthesis, their relationship.
  • Chemosynthesis.
    • Role chemosynthetic bacteria on Earth.
  • Genetic information in the cell.
    • Genes, genetic code and its properties.
    • Matrix nature of biosynthesis reactions.
  • Biosynthesis of protein and nucleic acids.
  • Cell – genetic unit of living being.
    • Chromosomes, their structure (shape and size) and functions.
    • The number of chromosomes and their species constancy.
  • Somatic and sex cells.
    • The life cycle of a cell: interphase and mitosis.
    • Mitosis is the division of somatic cells.
    • Meiosis.
    • Phases of mitosis and meiosis.
    • Development of sex cells in plants and animals.
    • Cell division is the basis for growth, development and reproduction of organisms.
  • The role of meiosis and mitosis

Diversity of organisms: unicellular and multicellular;

autotrophs, heterotrophs, aerobes, anaerobes

  • Reproduction of organisms, its importance.
  • Methods of reproduction, similarities and the difference between sexual and asexual reproduction.
  • Fertilization in flowering plants and vertebrates.
  • External and internal fertilization.
  • Ontogenesis and its inherent patterns.
  • Embryonic and postembryonic development of organisms.
  • Causes of developmental disorders organisms.

Genetics

  • Genetics and its tasks.
  • Heredity and variability – properties organisms.
  • Methods of genetics.
  • Basic genetic concepts and symbols.
  • Chromosomal theory of heredity.
  • Modern ideas about the gene and genome.
  • Patterns of heredity, their cytological basis.
  • The patterns of inheritance established by G. Mendel, their cytological genetic principles (mono- and dihybrid crossing).
  • T. Morgan’s laws: linked inheritance of traits, disruption of gene linkage.
  • Genetics sex.
  • Inheritance of sex-linked traits.
  • Interaction of genes.
  • Genotype as an integral system.
  • Human genetics.
  • Methods of study Human genetics.
  • Solving genetic problems.
  • Drawing up diagrams crossing.
  • Patterns Non-hereditary variability. (modification) variability.
  • Norm of reaction.
  • Hereditary variability: mutational, combinatorial.
  • Types of mutations and their causes.
  • The importance of variability in the life of organisms and in evolution.
  • The importance of genetics for medicine.
  • Hereditary human diseases, their causes, prevention.
  • Harmful effects of mutagens, alcohol, drugs, nicotine on genetic cell apparatus.
  • Protection of the environment from contamination by mutagens.
  • Identification sources of mutagens in the environment (indirectly) and assessment of possible consequences of their influence on their own organism
  • Selection, its tasks and practical significance. N. I. Vavilov’s contribution to the development of selection: the doctrine of the centers of diversity and origin of cultivated plants, the law homologous series in hereditary variability.
  • Methods of selection and their genetic foundations.
  • Methods of breeding new plant varieties, animal breeds, microorganism strains.
  • The importance of genetics for selection.
  • Biological principles of growing crops and domestic plants animals.
  • Biotechnology, its directions.
  • Cellular and genetic engineering, cloning.
  • The role of cell theory in the formation and development biotechnology.
  • The importance of biotechnology for the development of selection, agriculture, microbiological industry, preservation of the gene pool planets.
  • Ethical aspects of the development of some studies in biotechnology (human cloning, targeted genome editing)

The system and diversity of the organic world

  • Diversity of organisms.
  • The importance of the works of K. Linnaeus and J-B. Lamarck.
  • The main systematic (taxonomic) categories are: species, genus, family, detachment (order), class, type (department), kingdom; their subordination.
  • Viruses – non-cellular life forms.
    • Measures to prevent the spread of viral diseases.
  • Kingdom Bacteria, structure, vital activity, reproduction, role in nature. Bacteria – pathogens of diseases of plants, animals, humans.
  • Prevention of diseases caused by bacteria Kingdom Fungi, structure, vital activity, reproduction.
  • Use of mushrooms for obtaining food and medicine.
  • Recognition of edible and poisonous mushrooms.
  • Lichens, their diversity, structural features and vital activity.
  • The role of fungi and lichens in nature.
  • The Kingdom of Plants.
    • Structure (tissues, cells, organs), vital activity and reproduction of a plant organism (using angiosperms as an example).
    • Recognition (in pictures) of plant organs.
    • Diversity plants.
    • Main divisions of plants.
    • Classes of angiosperms, the role of plants in nature and human life.
  • Animal kingdom.
    • Unicellular and multicellular animals.
    • Characteristics of the main types of invertebrates, classes of arthropods.
    • Features of structure, life, reproduction, role in nature and human life.
    • Chordate animals.
    • Characteristics of the main classes.
    • Role in nature and human life.
    • Recognition (in pictures) of organs and organ systems in animals

The human body and its health

  • Tissues.
  • Structure and vital functions of organs and organ systems: digestion, respiration, excretion.
  • Recognition (in pictures) of tissues, organs, organ systems.
  • Structure and vital functions of organs and systems organs: musculoskeletal, integumentary, blood circulation, lymph drainage.
  • Reproduction and development of humans.
  • Recognition (in pictures) of organs and organ systems.
  • The internal environment of the human body. Blood groups.
  • Blood transfusion. Immunity.
  • Metabolism and energy conversion in the human body.
  • Vitamins.
  • Nervous and endocrine systems.
  • Neurohumoral regulation of vital processes of the body as the basis of its integrity, connection with the environment.
  • Analyzers.
  • Sense organs, their role in the body.
  • Structure and functions.
  • Higher nervous activity.
  • Sleep, its meaning.
  • Consciousness, memory, emotions, speech, thinking.
  • Peculiarities of the human psyche. Personal and public hygiene, healthy lifestyle.
  • Prevention of infectious diseases (viral, bacterial, fungal, animal-induced).
  • Prevention traumatism, first aid techniques.
  • Mental and physical health of a person.
  • Health factors (auto-training, hardening, physical activity).
  • Risk factors (stress, physical inactivity, overwork, hypothermia).
  • Bad and good habits.
  • Dependence of human health on the state of the environment.
  • Compliance with sanitary and hygienic norms and rules of a healthy lifestyle.
  • Human reproductive health.
  • Consequences of alcohol influence, nicotine, drugs on the development of the human embryo.

Evolution of living nature

  • The species and its criteria.
  • The population is a structural unit of the species and an elementary unit of evolution.
  • Microevolution.
    • Formation of new species.
    • Methods of speciation.
    • Preservation of species diversity as a basis for the sustainability of the biosphere.
    • Development of evolutionary ideas.
    • The significance of Ch. Darwin.
    • Interrelation of the driving forces of evolution.
    • Forms of natural selection, types of struggle for existence.
    • Synthetic theory of evolution.
    • Elementary factors of evolution.
    • Research of S.S. Chetverikov.
    • The role of evolutionary theory in the formation of the modern scientific picture of the world.
    • Evidence of the evolution of living nature.
    • Results of evolution: adaptation of organisms to the environment, diversity of species.
  • Macroevolution.
    • Directions and paths of evolution (A.N. Severtsov, P.P. Shmalgauzen).
    • Biological progress and regression, aromorphosis, idioadaptation, degeneration.
    • Causes of biological progress and regression.
    • Hypotheses about the origin of life on Earth.
    • The complication of living organisms on Earth in the process of evolution.
    • The origin of man. Man as a species, his place in the system of the organic world.
    • Hypotheses of the origin of modern man.
    • Driving forces and stages of human evolution.
    • Human races, their genetic relationship.
    • Biosocial nature of man.
    • Social and natural environments, human adaptations to them.
  • Ecosystems and their inherent patterns. Habitats of organisms.
    • Ecological factors: abiotic, biotic. Anthropogenic factor.
    • Their importance.
    • Ecosystem (biogeocenosis), its components: producers, consumers, Reducers, their role.
    • Species and spatial structure of the ecosystem.
    • Trophic levels.
    • Food chains and networks, their links.
    • Rules of ecological pyramids.
    • Drawing up diagrams of the transfer of substances and energy (food chains).
    • Diversity of ecosystems (biogeocenoses).
    • Self-development and change of ecosystems.
    • Ecosystem stability and dynamics.
  • Biodiversity, self-regulation and circulation of substances – the basis of sustainable development ecosystems.
  • Causes of stability and change of ecosystems.
  • Changes in ecosystems under the influence of human activity.
  • Agroecosystems, the main differences from natural ecosystems.
  • The biosphere is a global ecosystem.
  • The doctrine V.I.Vernadsky about the biosphere.
  • Living matter, its functions.
  • Features of biomass distribution on Earth.
  • Biological cycle and energy conversion in the biosphere, the role of organisms of different kingdoms in it.
  • Evolution of the biosphere.
  • Global changes in the biosphere caused by the activity of man (violation of the ozone screen, acid rain, greenhouse effect, etc.).
  • Problems of sustainable development of the biosphere.
  • Rules of conduct in the natural environment

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